Ambika Rao was the associate director and star of several Malayalam films including 'Kumbalangi Nights', 'Meesha Madhavan', 'Anuraga Karikin Vellam' and 'Virus', among many other films.
Ambika's death was confirmed by film producer NM Badusha who took to social media to share the news.
The actor had to undergo dialysis twice a week for the past two years, and sought financial help from well-wishers in December 2020.
Ambika's percussionist brother Aji had previously been taking care of her.